Recent Publications
by Heiman, GA.
Found 78 publication(s).
Up-to-date.
Tsetsos, F., Yu, D., Sul, J. H., Huang, A. Y., Illmann, C., Osiecki, L., Darrow, S. M., Hirschtritt, M. E., Greenberg, E., Muller-Vahl, K. R., Stuhrmann, M., Dion, Y., Rouleau, G. A., Aschauer, H., Stamenkovic, M., Schlögelhofer, M., Sandor, P., Barr, C. L., Grados, M. A., Singer, H. S., Nöthen, M. M., Hebebrand, J., Hinney, A., King, R. A., Fernandez, T. V., Barta, C., Tarnok, Z., Nagy, P., Depienne, C., Worbe, Y., Hartmann, A., Budman, C. L., Rizzo, R., Lyon, G. J., McMahon, W. M., Batterson, J. R., Cath, D. C., Malaty, I. A., Okun, M. S., Berlin, C., Woods, D. W., Lee, P. C., Jankovic, J., Robertson, M. M., Gilbert, D. L., Brown, L. W., Coffey, B. J., Dietrich, A., Hoekstra, P. J., Kuperman, S., Zinner, S. H., Wagner, M., Knowles, J. A., Jeremy Willsey, A., Tischfield, J. A., Heiman, G. A., Cox, N. J., Freimer, N. B., Neale, B. M., Davis, L. K., Coppola, G., Mathews, C. A., Scharf, J. M., Paschou, P., ,, Barr, C. L., Batterson, J. R., Berlin, C., Budman, C. L., Cath, D. C., Coppola, G., Cox, N. J., Darrow, S., Davis, L. K., Dion, Y., Freimer, N. B., Grados, M. A., Greenberg, E., Hirschtritt, M. E., Huang, A. Y., Illmann, C., King, R. A., Kurlan, R., Leckman, J. F., Lyon, G. J., Malaty, I. A., Mathews, C. A., McMahon, W. M., Neale, B. M., Okun, M. S., Osiecki, L., Robertson, M. M., Rouleau, G. A., Sandor, P., Scharf, J. M., Singer, H. S., Smit, J. H., Sul, J. H., Yu, D., ,, Aschauer, H. A. H., Barta, C., Budman, C. L., Cath, D. C., Depienne, C., Hartmann, A., Hebebrand, J., Konstantinidis, A., Mathews, C. A., Müller-Vahl, K., Nagy, P., Nöthen, M. M., Paschou, P., Rizzo, R., Rouleau, G. A., Sandor, P., Scharf, J. M., Schlögelhofer, M., Stamenkovic, M., Stuhrmann, M., Tsetsos, F., Tarnok, Z., Wolanczyk, T., Worbe, Y., ,, Brown, L., Cheon, K. A., Coffey, B. J., Dietrich, A., Fernandez, T. V., Garcia-Delgar, B., Gilbert, D., Grice, D. E., Hagstrøm, J., Hedderly, T., Heiman, G. A., Heyman, I., Hoekstra, P. J., Huyser, C., Kim, Y. K., Kim, Y. S., King, R. A., Koh, Y. J., Kook, S., Kuperman, S., Leventhal, B. L., Madruga-Garrido, M., Mir, P., Morer, A., Münchau, A., Plessen, K. J., Roessner, V., Shin, E. Y., Song, D. H., Song, J., Tischfield, J. A., Willsey, A. J., Zinner, S., ,, Aschauer, H., Barr, C. L., Barta, C., Batterson, J. R., Berlin, C., Brown, L., Budman, C. L., Cath, D. C., Coffey, B. J., Coppola, G., Cox, N. J., Darrow, S., Davis, L. K., Depienne, C., Dietrich, A., Dion, Y., Fernandez, T., Freimer, N. B., Gilbert, D., Grados, M. A., Greenberg, E., Hartmann, A., Hebebrand, J., Heiman, G., Hirschtritt, M. E., Hoekstra, P., Huang, A. Y., Illmann, C., Jankovic, J., King, R. A., Kuperman, S., Lee, P. C., Lyon, G. J., Malaty, I. A., Mathews, C. A., McMahon, W. M., Müller-Vahl, K., Nagy, P., Neale, B. M., Nöthen, M. M., Okun, M. S., Osiecki, L., Paschou, P., Rizzo, R., Robertson, M. M., Rouleau, G. A., Sandor, P., Scharf, J. M., Schlögelhofer, M., Singer, H. S., Stamenkovic, M., Stuhrmann, M., Sul, J. H., Tarnok, Z., Tischfield, J., Tsetsos, F., Willsey, A. J., Woods, D., Worbe, Y., Yu, D., & Zinner, S. (2021). Synaptic processes and immune-related pathways implicated in Tourette syndrome. Translational psychiatry, 11, 56. PubMed
Simone, L., Khan, S., Ciarlariello, M., Lin, J., Trackman, S., Heiman, G. A., & Ashkinadze, E. (2021). Reproductive male partner testing when the female is identified to be a genetic disease carrier. Prenatal diagnosis, 41, 21-27. PubMed
Cao, X., Zhang, Y., Abdulkadir, M., Deng, L., Fernandez, T. V., Garcia-Delgar, B., Hagstrøm, J., Hoekstra, P. J., King, R. A., Koesterich, J., Kuperman, S., Morer, A., Nasello, C., Plessen, K. J., Thackray, J. K., Zhou, L., ,, Dietrich, A., Tischfield, J. A., Heiman, G. A., & Xing, J. (2021). Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Molecular psychiatry. PubMed
Heiman, G. A., Rispoli, J., Seymour, C., Leckman, J. F., King, R. A., & Fernandez, T. V. (2020). Empiric Recurrence Risk Estimates for Chronic Tic Disorders: Implications for Genetic Counseling. Frontiers in neurology, 11, 770. PubMed
Choi, H., Detyniecki, K., Bazil, C., Thornton, S., Crosta, P., Tolba, H., Muneeb, M., Hirsch, L. J., Heinzen, E. L., Sen, A., Depondt, C., Perucca, P., Heiman, G. A., & , (2020). Development and validation of a predictive model of drug-resistant genetic generalized epilepsy. Neurology, 95, e2150-e2160. PubMed
Yu, D., Sul, J. H., Tsetsos, F., Nawaz, M. S., Huang, A. Y., Zelaya, I., Illmann, C., Osiecki, L., Darrow, S. M., Hirschtritt, M. E., Greenberg, E., Muller-Vahl, K. R., Stuhrmann, M., Dion, Y., Rouleau, G., Aschauer, H., Stamenkovic, M., Schlögelhofer, M., Sandor, P., Barr, C. L., Grados, M., Singer, H. S., Nöthen, M. M., Hebebrand, J., Hinney, A., King, R. A., Fernandez, T. V., Barta, C., Tarnok, Z., Nagy, P., Depienne, C., Worbe, Y., Hartmann, A., Budman, C. L., Rizzo, R., Lyon, G. J., McMahon, W. M., Batterson, J. R., Cath, D. C., Malaty, I. A., Okun, M. S., Berlin, C., Woods, D. W., Lee, P. C., Jankovic, J., Robertson, M. M., Gilbert, D. L., Brown, L. W., Coffey, B. J., Dietrich, A., Hoekstra, P. J., Kuperman, S., Zinner, S. H., Luðvigsson, P., Sæmundsen, E., Thorarensen,, Atzmon, G., Barzilai, N., Wagner, M., Moessner, R., Ophoff, R., Pato, C. N., Pato, M. T., Knowles, J. A., Roffman, J. L., Smoller, J. W., Buckner, R. L., Willsey, A. J., Tischfield, J. A., Heiman, G. A., Stefansson, H., Stefansson, K., Posthuma, D., Cox, N. J., Pauls, D. L., Freimer, N. B., Neale, B. M., Davis, L. K., Paschou, P., Coppola, G., Mathews, C. A., Scharf, J. M., & , (2019). Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies. The American journal of psychiatry, 176, 217-227. PubMed
,, & , (2019). Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. Cell, 179, 1469-1482.e11. PubMed
Abdulkadir, M., Mathews, C. A., Scharf, J. M., Yu, D., Tischfield, J. A., Heiman, G. A., Hoekstra, P. J., & Dietrich, A. (2019). Polygenic Risk Scores Derived From a Tourette Syndrome Genome-wide Association Study Predict Presence of Tics in the Avon Longitudinal Study of Parents and Children Cohort. Biological psychiatry, 85, 298-304. PubMed
Wang, S., Mandell, J. D., Kumar, Y., Sun, N., Morris, M. T., Arbelaez, J., Nasello, C., Dong, S., Duhn, C., Zhao, X., Yang, Z., Padmanabhuni, S. S., Yu, D., King, R. A., Dietrich, A., Khalifa, N., Dahl, N., Huang, A. Y., Neale, B. M., Coppola, G., Mathews, C. A., Scharf, J. M., ,, ,, ,, Fernandez, T. V., Buxbaum, J. D., De Rubeis, S., Grice, D. E., Xing, J., Heiman, G. A., Tischfield, J. A., Paschou, P., Willsey, A. J., & State, M. W. (2018). De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis. Cell reports, 25, 3544. PubMed
Sun, N., Nasello, C., Deng, L., Wang, N., Zhang, Y., Xu, Z., Song, Z., Kwan, K., King, R. A., Pang, Z. P., Xing, J., Heiman, G. A., & Tischfield, J. A. (2018). The PNKD gene is associated with Tourette Disorder or Tic disorder in a multiplex family. Molecular psychiatry, 23, 1487-1495. PubMed
Insel, B. J., Ottman, R., & Heiman, G. A. (2018). Mood disorders in familial epilepsy: A test of shared etiology. Epilepsia, 59, 431-439. PubMed
Wang, S., Mandell, J. D., Kumar, Y., Sun, N., Morris, M. T., Arbelaez, J., Nasello, C., Dong, S., Duhn, C., Zhao, X., Yang, Z., Padmanabhuni, S. S., Yu, D., King, R. A., Dietrich, A., Khalifa, N., Dahl, N., Huang, A. Y., Neale, B. M., Coppola, G., Mathews, C. A., Scharf, J. M., ,, ,, ,, Fernandez, T. V., Buxbaum, J. D., De Rubeis, S., Grice, D. E., Xing, J., Heiman, G. A., Tischfield, J. A., Paschou, P., Willsey, A. J., & State, M. W. (2018). De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis. Cell reports, 24, 3441-3454.e12. PubMed
Abdulkadir, M., Londono, D., Gordon, D., Fernandez, T. V., Brown, L. W., Cheon, K. A., Coffey, B. J., Elzerman, L., Fremer, C., Fründt, O., Garcia-Delgar, B., Gilbert, D. L., Grice, D. E., Hedderly, T., Heyman, I., Hong, H. J., Huyser, C., Ibanez-Gomez, L., Jakubovski, E., Kim, Y. K., Kim, Y. S., Koh, Y. J., Kook, S., Kuperman, S., Leventhal, B., Ludolph, A. G., Madruga-Garrido, M., Maras, A., Mir, P., Morer, A., Müller-Vahl, K., Münchau, A., Murphy, T. L., Plessen, K. J., Roessner, V., Shin, E. Y., Song, D. H., Song, J., Tübing, J., Van den Ban, E., Visscher, F., Wanderer, S., Woods, M., Zinner, S. H., King, R. A., Tischfield, J. A., Heiman, G. A., Hoekstra, P. J., & Dietrich, A. (2018). Investigation of previously implicated genetic variants in chronic tic disorders: a transmission disequilibrium test approach. European archives of psychiatry and clinical neuroscience, 268, 301-316. PubMed
Willsey, A. J., Fernandez, T. V., Yu, D., King, R. A., Dietrich, A., Xing, J., Sanders, S. J., Mandell, J. D., Huang, A. Y., Richer, P., Smith, L., Dong, S., Samocha, K. E., ,, ,, Neale, B. M., Coppola, G., Mathews, C. A., Tischfield, J. A., Scharf, J. M., State, M. W., & Heiman, G. A. (2017). De Novo Coding Variants Are Strongly Associated with Tourette Disorder. Neuron, 94, 486-499.e9. PubMed
Gordon, D., Londono, D., Patel, P., Kim, W., Finch, S. J., & Heiman, G. A. (2016). An Analytic Solution to the Computation of Power and Sample Size for Genetic Association Studies under a Pleiotropic Mode of Inheritance. Human heredity, 81, 194-209. PubMed
Choi, H., Hayat, M. J., Zhang, R., Hirsch, L. J., Bazil, C. W., Mendiratta, A., Kato, K., Javed, A., Legge, A. W., Buchsbaum, R., Resor, S., & Heiman, G. A. (2016). Drug-resistant epilepsy in adults: Outcome trajectories after failure of two medications. Epilepsia, 57, 1152-60. PubMed
Abdulkadir, M., Tischfield, J. A., King, R. A., Fernandez, T. V., Brown, L. W., Cheon, K. A., Coffey, B. J., De Bruijn, S. F., Elzerman, L., Garcia-Delgar, B., Gilbert, D. L., Grice, D. E., Hagstrøm, J., Hedderly, T., Heyman, I., Hong, H. J., Huyser, C., Ibanez-Gomez, L., Kim, Y. K., Kim, Y. S., Koh, Y. J., Kook, S., Kuperman, S., Lamerz, A., Leventhal, B., Ludolph, A. G., Madruga-Garrido, M., Maras, A., Messchendorp, M. D., Mir, P., Morer, A., Münchau, A., Murphy, T. L., Openneer, T. J., Plessen, K. J., Rath, J. J., Roessner, V., Fründt, O., Shin, E. Y., Sival, D. A., Song, D. H., Song, J., Stolte, A. M., Tübing, J., Van den Ban, E., Visscher, F., Wanderer, S., Woods, M., Zinner, S. H., State, M. W., Heiman, G. A., Hoekstra, P. J., & Dietrich, A. (2016). Pre- and perinatal complications in relation to Tourette syndrome and co-occurring obsessive-compulsive disorder and attention-deficit/hyperactivity disorder. Journal of psychiatric research, 82, 126-35. PubMed
Choi, H., Hayat, M. J., Zhang, R., Hirsch, L. J., Bazil, C., Mendiratta, A., Kato, K., Javed, A., Legge, A. W., Buchsbaum, R., Resor, S., & Heiman, G. (2016). In response: Drug-resistant epilepsy in adults: outcome trajectories after failure of two medications. Epilepsia, 57, 1526-7. PubMed
Sun, N., Tischfield, J. A., King, R. A., & Heiman, G. A. (2016). Functional Evaluations of Genes Disrupted in Patients with Tourette's Disorder. Frontiers in psychiatry, 7, 11. PubMed
Alexander, J., Potamianou, H., Xing, J., Deng, L., Karagiannidis, I., Tsetsos, F., Drineas, P., Tarnok, Z., Rizzo, R., Wolanczyk, T., Farkas, L., Nagy, P., Szymanska, U., Androutsos, C., Tsironi, V., Koumoula, A., Barta, C., ,, Sandor, P., Barr, C. L., Tischfield, J., Paschou, P., Heiman, G. A., & Georgitsi, M. (2016). Targeted Re-Sequencing Approach of Candidate Genes Implicates Rare Potentially Functional Variants in Tourette Syndrome Etiology. Frontiers in neuroscience, 10, 428. PubMed
De Leeuw, C., Goudriaan, A., Smit, A. B., Yu, D., Mathews, C. A., Scharf, J. M., ,, Verheijen, M. H., & Posthuma, D. (2015). Involvement of astrocyte metabolic coupling in Tourette syndrome pathogenesis. European journal of human genetics : EJHG, 23, 1519-22. PubMed
Huertas-Fernández, I., Gómez-Garre, P., Madruga-Garrido, M., Bernal-Bernal, I., Bonilla-Toribio, M., Martín-Rodríguez, J. F., Cáceres-Redondo, M. T., Vargas-González, L., Carrillo, F., Pascual, A., Tischfield, J. A., King, R. A., Heiman, G. A., & Mir, P. (2015). GDNF gene is associated with tourette syndrome in a family study. Movement disorders : official journal of the Movement Disorder Society, 30, 1115-20. PubMed
Dietrich, A., Fernandez, T. V., King, R. A., State, M. W., Tischfield, J. A., Hoekstra, P. J., Heiman, G. A., & , (2015). The Tourette International Collaborative Genetics (TIC Genetics) study, finding the genes causing Tourette syndrome: objectives and methods. European child & adolescent psychiatry, 24, 141-51. PubMed
Yu, D., Mathews, C. A., Scharf, J. M., Neale, B. M., Davis, L. K., Gamazon, E. R., Derks, E. M., Evans, P., Edlund, C. K., Crane, J., Fagerness, J. A., Osiecki, L., Gallagher, P., Gerber, G., Haddad, S., Illmann, C., McGrath, L. M., Mayerfeld, C., Arepalli, S., Barlassina, C., Barr, C. L., Bellodi, L., Benarroch, F., Berrió, G. B., Bienvenu, O. J., Black, D. W., Bloch, M. H., Brentani, H., Bruun, R. D., Budman, C. L., Camarena, B., Campbell, D. D., Cappi, C., Silgado, J. C., Cavallini, M. C., Chavira, D. A., Chouinard, S., Cook, E. H., Cookson, M. R., Coric, V., Cullen, B., Cusi, D., Delorme, R., Denys, D., Dion, Y., Eapen, V., Egberts, K., Falkai, P., Fernandez, T., Fournier, E., Garrido, H., Geller, D., Gilbert, D. L., Girard, S. L., Grabe, H. J., Grados, M. A., Greenberg, B. D., Gross-Tsur, V., Grünblatt, E., Hardy, J., Heiman, G. A., Hemmings, S. M., Herrera, L. D., Hezel, D. M., Hoekstra, P. J., Jankovic, J., Kennedy, J. L., King, R. A., Konkashbaev, A. I., Kremeyer, B., Kurlan, R., Lanzagorta, N., Leboyer, M., Leckman, J. F., Lennertz, L., Liu, C., Lochner, C., Lowe, T. L., Lupoli, S., Macciardi, F., Maier, W., Manunta, P., Marconi, M., McCracken, J. T., Mesa Restrepo, S. C., Moessner, R., Moorjani, P., Morgan, J., Muller, H., Murphy, D. L., Naarden, A. L., Nurmi, E., Ochoa, W. C., Ophoff, R. A., Pakstis, A. J., Pato, M. T., Pato, C. N., Piacentini, J., Pittenger, C., Pollak, Y., Rauch, S. L., Renner, T., Reus, V. I., Richter, M. A., Riddle, M. A., Robertson, M. M., Romero, R., Rosário, M. C., Rosenberg, D., Ruhrmann, S., Sabatti, C., Salvi, E., Sampaio, A. S., Samuels, J., Sandor, P., Service, S. K., Sheppard, B., Singer, H. S., Smit, J. H., Stein, D. J., Strengman, E., Tischfield, J. A., Turiel, M., Valencia Duarte, A. V., Vallada, H., Veenstra-VanderWeele, J., Walitza, S., Wang, Y., Weale, M., Weiss, R., Wendland, J. R., Westenberg, H. G., Shugart, Y. Y., Hounie, A. G., Miguel, E. C., Nicolini, H., Wagner, M., Ruiz-Linares, A., Cath, D. C., McMahon, W., Posthuma, D., Oostra, B. A., Nestadt, G., Rouleau, G. A., Purcell, S., Jenike, M. A., Heutink, P., Hanna, G. L., Conti, D. V., Arnold, P. D., Freimer, N. B., Stewart, S. E., Knowles, J. A., Cox, N. J., & Pauls, D. L. (2015). Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. The American journal of psychiatry, 172, 82-93. PubMed
McGrath, L. M., Yu, D., Marshall, C., Davis, L. K., Thiruvahindrapuram, B., Li, B., Cappi, C., Gerber, G., Wolf, A., Schroeder, F. A., Osiecki, L., O'Dushlaine, C., Kirby, A., Illmann, C., Haddad, S., Gallagher, P., Fagerness, J. A., Barr, C. L., Bellodi, L., Benarroch, F., Bienvenu, O. J., Black, D. W., Bloch, M. H., Bruun, R. D., Budman, C. L., Camarena, B., Cath, D. C., Cavallini, M. C., Chouinard, S., Coric, V., Cullen, B., Delorme, R., Denys, D., Derks, E. M., Dion, Y., Rosário, M. C., Eapen, V., Evans, P., Falkai, P., Fernandez, T. V., Garrido, H., Geller, D., Grabe, H. J., Grados, M. A., Greenberg, B. D., Gross-Tsur, V., Grünblatt, E., Heiman, G. A., Hemmings, S. M., Herrera, L. D., Hounie, A. G., Jankovic, J., Kennedy, J. L., King, R. A., Kurlan, R., Lanzagorta, N., Leboyer, M., Leckman, J. F., Lennertz, L., Lochner, C., Lowe, T. L., Lyon, G. J., Macciardi, F., Maier, W., McCracken, J. T., McMahon, W., Murphy, D. L., Naarden, A. L., Neale, B. M., Nurmi, E., Pakstis, A. J., Pato, M. T., Pato, C. N., Piacentini, J., Pittenger, C., Pollak, Y., Reus, V. I., Richter, M. A., Riddle, M., Robertson, M. M., Rosenberg, D., Rouleau, G. A., Ruhrmann, S., Sampaio, A. S., Samuels, J., Sandor, P., Sheppard, B., Singer, H. S., Smit, J. H., Stein, D. J., Tischfield, J. A., Vallada, H., Veenstra-VanderWeele, J., Walitza, S., Wang, Y., Wendland, J. R., Shugart, Y. Y., Miguel, E. C., Nicolini, H., Oostra, B. A., Moessner, R., Wagner, M., Ruiz-Linares, A., Heutink, P., Nestadt, G., Freimer, N., Petryshen, T., Posthuma, D., Jenike, M. A., Cox, N. J., Hanna, G. L., Brentani, H., Scherer, S. W., Arnold, P. D., Stewart, S. E., Mathews, C. A., Knowles, J. A., Cook, E. H., Pauls, D. L., Wang, K., & Scharf, J. M. (2014). Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study. Journal of the American Academy of Child and Adolescent Psychiatry, 53, 910-9. PubMed
Paschou, P., Fernandez, T. V., Sharp, F., Heiman, G. A., & Hoekstra, P. J. (2013). Genetic susceptibility and neurotransmitters in Tourette syndrome. International review of neurobiology, 112, 155-77. PubMed
Davis, L. K., Yu, D., Keenan, C. L., Gamazon, E. R., Konkashbaev, A. I., Derks, E. M., Neale, B. M., Yang, J., Lee, S. H., Evans, P., Barr, C. L., Bellodi, L., Benarroch, F., Berrio, G. B., Bienvenu, O. J., Bloch, M. H., Blom, R. M., Bruun, R. D., Budman, C. L., Camarena, B., Campbell, D., Cappi, C., Cardona Silgado, J. C., Cath, D. C., Cavallini, M. C., Chavira, D. A., Chouinard, S., Conti, D. V., Cook, E. H., Coric, V., Cullen, B. A., Deforce, D., Delorme, R., Dion, Y., Edlund, C. K., Egberts, K., Falkai, P., Fernandez, T. V., Gallagher, P. J., Garrido, H., Geller, D., Girard, S. L., Grabe, H. J., Grados, M. A., Greenberg, B. D., Gross-Tsur, V., Haddad, S., Heiman, G. A., Hemmings, S. M., Hounie, A. G., Illmann, C., Jankovic, J., Jenike, M. A., Kennedy, J. L., King, R. A., Kremeyer, B., Kurlan, R., Lanzagorta, N., Leboyer, M., Leckman, J. F., Lennertz, L., Liu, C., Lochner, C., Lowe, T. L., Macciardi, F., McCracken, J. T., McGrath, L. M., Mesa Restrepo, S. C., Moessner, R., Morgan, J., Muller, H., Murphy, D. L., Naarden, A. L., Ochoa, W. C., Ophoff, R. A., Osiecki, L., Pakstis, A. J., Pato, M. T., Pato, C. N., Piacentini, J., Pittenger, C., Pollak, Y., Rauch, S. L., Renner, T. J., Reus, V. I., Richter, M. A., Riddle, M. A., Robertson, M. M., Romero, R., Rosàrio, M. C., Rosenberg, D., Rouleau, G. A., Ruhrmann, S., Ruiz-Linares, A., Sampaio, A. S., Samuels, J., Sandor, P., Sheppard, B., Singer, H. S., Smit, J. H., Stein, D. J., Strengman, E., Tischfield, J. A., Valencia Duarte, A. V., Vallada, H., Van Nieuwerburgh, F., Veenstra-Vanderweele, J., Walitza, S., Wang, Y., Wendland, J. R., Westenberg, H. G., Shugart, Y. Y., Miguel, E. C., McMahon, W., Wagner, M., Nicolini, H., Posthuma, D., Hanna, G. L., Heutink, P., Denys, D., Arnold, P. D., Oostra, B. A., Nestadt, G., Freimer, N. B., Pauls, D. L., Wray, N. R., Stewart, S. E., Mathews, C. A., Knowles, J. A., Cox, N. J., & Scharf, J. M. (2013). Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS genetics, 9, e1003864. PubMed
Moya, P. R., Dodman, N. H., Timpano, K. R., Rubenstein, L. M., Rana, Z., Fried, R. L., Reichardt, L. F., Heiman, G. A., Tischfield, J. A., King, R. A., Galdzicka, M., Ginns, E. I., & Wendland, J. R. (2013). Rare missense neuronal cadherin gene (CDH2) variants in specific obsessive-compulsive disorder and Tourette disorder phenotypes. European journal of human genetics : EJHG, 21, 850-4. PubMed
Moya, P. R., Wendland, J. R., Rubenstein, L. M., Timpano, K. R., Heiman, G. A., Tischfield, J. A., King, R. A., Andrews, A. M., Ramamoorthy, S., McMahon, F. J., & Murphy, D. L. (2013). Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder. Movement disorders : official journal of the Movement Disorder Society, 28, 1263-70. PubMed
Scharf, J. M., Yu, D., Mathews, C. A., Neale, B. M., Stewart, S. E., Fagerness, J. A., Evans, P., Gamazon, E., Edlund, C. K., Service, S. K., Tikhomirov, A., Osiecki, L., Illmann, C., Pluzhnikov, A., Konkashbaev, A., Davis, L. K., Han, B., Crane, J., Moorjani, P., Crenshaw, A. T., Parkin, M. A., Reus, V. I., Lowe, T. L., Rangel-Lugo, M., Chouinard, S., Dion, Y., Girard, S., Cath, D. C., Smit, J. H., King, R. A., Fernandez, T. V., Leckman, J. F., Kidd, K. K., Kidd, J. R., Pakstis, A. J., State, M. W., Herrera, L. D., Romero, R., Fournier, E., Sandor, P., Barr, C. L., Phan, N., Gross-Tsur, V., Benarroch, F., Pollak, Y., Budman, C. L., Bruun, R. D., Erenberg, G., Naarden, A. L., Lee, P. C., Weiss, N., Kremeyer, B., Berrío, G. B., Campbell, D. D., Cardona Silgado, J. C., Ochoa, W. C., Mesa Restrepo, S. C., Muller, H., Valencia Duarte, A. V., Lyon, G. J., Leppert, M., Morgan, J., Weiss, R., Grados, M. A., Anderson, K., Davarya, S., Singer, H., Walkup, J., Jankovic, J., Tischfield, J. A., Heiman, G. A., Gilbert, D. L., Hoekstra, P. J., Robertson, M. M., Kurlan, R., Liu, C., Gibbs, J. R., Singleton, A., ,, Hardy, J., ,, Strengman, E., Ophoff, R. A., Wagner, M., Moessner, R., Mirel, D. B., Posthuma, D., Sabatti, C., Eskin, E., Conti, D. V., Knowles, J. A., Ruiz-Linares, A., Rouleau, G. A., Purcell, S., Heutink, P., Oostra, B. A., McMahon, W. M., Freimer, N. B., Cox, N. J., & Pauls, D. L. (2013). Genome-wide association study of Tourette's syndrome. Molecular psychiatry, 18, 721-8. PubMed
Fernandez, T. V., Sanders, S. J., Yurkiewicz, I. R., Ercan-Sencicek, A. G., Kim, Y. S., Fishman, D. O., Raubeson, M. J., Song, Y., Yasuno, K., Ho, W. S., Bilguvar, K., Glessner, J., Chu, S. H., Leckman, J. F., King, R. A., Gilbert, D. L., Heiman, G. A., Tischfield, J. A., Hoekstra, P. J., Devlin, B., Hakonarson, H., Mane, S. M., Günel, M., & State, M. W. (2012). Rare copy number variants in tourette syndrome disrupt genes in histaminergic pathways and overlap with autism. Biological psychiatry, 71, 392-402. PubMed
Gorroochurn, P., Hodge, S. E., Heiman, G. A., & Greenberg, D. A. (2011). An improved delta-centralization method for population stratification. Human heredity, 71, 180-5. PubMed
Shanker, V., Groves, M., Heiman, G., Palmese, C., Saunders-Pullman, R., Ozelius, L., Raymond, D., & Bressman, S. (2011). Mood and cognition in leucine-rich repeat kinase 2 G2019S Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 26, 1875-80. PubMed
Choi, H., Heiman, G. A., Munger Clary, H., Etienne, M., Resor, S. R., & Hauser, W. A. (2011). Seizure remission in adults with long-standing intractable epilepsy: an extended follow-up. Epilepsy research, 93, 115-9. PubMed
Choi, H., Wong, J. B., Mendiratta, A., Heiman, G. A., & Hamberger, M. J. (2011). Numeracy and framing bias in epilepsy. Epilepsy & behavior : E&B, 20, 29-33. PubMed
Gorroochurn, P., Hodge, S. E., Heiman, G. A., & Greenberg, D. A. (2010). Comments on 'Delta-centralization fails to control for population stratification in genetic association studies'. Human heredity, 69, 295. PubMed
Heiman, G. A., Kamberakis, K., Gill, R., Kalachikov, S., Pedley, T. A., Hauser, W. A., & Ottman, R. (2010). Evaluation of depression risk in LGI1 mutation carriers. Epilepsia, 51, 1685-90. PubMed
Ercan-Sencicek, A. G., Stillman, A. A., Ghosh, A. K., Bilguvar, K., O'Roak, B. J., Mason, C. E., Abbott, T., Gupta, A., King, R. A., Pauls, D. L., Tischfield, J. A., Heiman, G. A., Singer, H. S., Gilbert, D. L., Hoekstra, P. J., Morgan, T. M., Loring, E., Yasuno, K., Fernandez, T., Sanders, S., Louvi, A., Cho, J. H., Mane, S., Colangelo, C. M., Biederer, T., Lifton, R. P., Gunel, M., & State, M. W. (2010). L-histidine decarboxylase and Tourette's syndrome. The New England journal of medicine, 362, 1901-8. PubMed
Logue, M. W., Durner, M., Heiman, G. A., Hodge, S. E., Hamilton, S. P., Knowles, J. A., Fyer, A. J., & Weissman, M. M. (2009). A linkage search for joint panic disorder/bipolar genes. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 150B, 1139-46. PubMed
Gorroochurn, P., Hodge, S. E., Heiman, G. A., & Greenberg, D. A. (2009). Comments on: review and evaluation of methods correcting for population stratification with a focus on underlying statistical principles. Human heredity, 67, 145-6. PubMed
Choi, H., Carlino, R., Heiman, G., Hauser, W. A., & Gilliam, F. G. (2009). Evaluation of duration of epilepsy prior to temporal lobe epilepsy surgery during the past two decades. Epilepsy research, 86, 224-7. PubMed
Bressman, S. B., Raymond, D., Fuchs, T., Heiman, G. A., Ozelius, L. J., & Saunders-Pullman, R. (2009). Mutations in THAP1 (DYT6) in early-onset dystonia: a genetic screening study. The Lancet. Neurology, 8, 441-6. PubMed
Heiman, G. A., King, R. A., & Tischfield, J. A. (2008). New Jersey Center for Tourette Syndrome sharing repository: methods and sample description. BMC medical genomics, 1, 58. PubMed
Choi, H., Heiman, G., Pandis, D., Cantero, J., Resor, S. R., Gilliam, F. G., & Hauser, W. A. (2008). Seizure remission and relapse in adults with intractable epilepsy: a cohort study. Epilepsia, 49, 1440-5. PubMed
Raymond, D., Saunders-Pullman, R., De Carvalho Aguiar, P., Schule, B., Kock, N., Friedman, J., Harris, J., Ford, B., Frucht, S., Heiman, G. A., Jennings, D., Doheny, D., Brin, M. F., De Leon Brin, D., Multhaupt-Buell, T., Lang, A. E., Kurlan, R., Klein, C., Ozelius, L., & Bressman, S. (2008). Phenotypic spectrum and sex effects in eleven myoclonus-dystonia families with epsilon-sarcoglycan mutations. Movement disorders : official journal of the Movement Disorder Society, 23, 588-92. PubMed
Heiman, G. A., Ogburn, E., Gorroochurn, P., Keyes, K. M., & Hasin, D. (2008). Evidence for a two-stage model of dependence using the NESARC and its implications for genetic association studies. Drug and alcohol dependence, 92, 258-66. PubMed
Gorroochurn, P., Hodge, S. E., Heiman, G. A., & Greenberg, D. A. (2007). A unified approach for quantifying, testing and correcting population stratification in case-control association studies. Human heredity, 64, 149-59. PubMed
Gorroochurn, P., Hodge, S. E., Heiman, G. A., Durner, M., & Greenberg, D. A. (2007). Non-replication of association studies: "pseudo-failures" to replicate? Genetics in medicine : official journal of the American College of Medical Genetics, 9, 325-31. PubMed
Heiman, G. A., Ottman, R., Saunders-Pullman, R. J., Ozelius, L. J., Risch, N. J., & Bressman, S. B. (2007). Obsessive-compulsive disorder is not a clinical manifestation of the DYT1 dystonia gene. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 144B, 361-4. PubMed
Hess, C. W., Raymond, D., Aguiar, P. D. E. C., Frucht, S., Shriberg, J., Heiman, G. A., Kurlan, R., Klein, C., Bressman, S. B., Ozelius, L. J., & Saunders-Pullman, R. (2007). Myoclonus-dystonia, obsessive-compulsive disorder, and alcohol dependence in SGCE mutation carriers. Neurology, 68, 522-4. PubMed
Fyer, A. J., Hamilton, S. P., Durner, M., Haghighi, F., Heiman, G. A., Costa, R., Evgrafov, O., Adams, P., De Leon, A. B., Taveras, N., Klein, D. F., Hodge, S. E., Weissman, M. M., & Knowles, J. A. (2006). A third-pass genome scan in panic disorder: evidence for multiple susceptibility loci. Biological psychiatry, 60, 388-401. PubMed
Gorroochurn, P., Heiman, G. A., Hodge, S. E., & Greenberg, D. A. (2006). Centralizing the non-central chi-square: A new method to correct for population stratification in genetic case-control association studies. Genetic epidemiology, 30, 277-89. PubMed
Heiman, G. A., Gorroochurn, P., Hodge, S. E., & Greenberg, D. A. (2005). Robustness of case-control studies to population stratification. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 14, 1579-80; author reply 1580-1. PubMed
Tsai, W. Y., Heiman, G. A., & Hodge, S. E. (2005). New simple tests for age-at-onset anticipation: application to panic disorder. Genetic epidemiology, 28, 256-60. PubMed
Gorroochurn, P., Hodge, S. E., Heiman, G., & Greenberg, D. A. (2004). Effect of population stratification on case-control association studies. II. False-positive rates and their limiting behavior as number of subpopulations increases. Human heredity, 58, 40-8. PubMed
Heiman, G. A., Hodge, S. E., Gorroochurn, P., Zhang, J., & Greenberg, D. A. (2004). Effect of population stratification on case-control association studies. I. Elevation in false positive rates and comparison to confounding risk ratios (a simulation study). Human heredity, 58, 30-9. PubMed
Heiman, G. A., Ottman, R., Saunders-Pullman, R. J., Ozelius, L. J., Risch, N. J., & Bressman, S. B. (2004). Increased risk for recurrent major depression in DYT1 dystonia mutation carriers. Neurology, 63, 631-7. PubMed
Hamilton, S. P., Slager, S. L., Mayo, D., Heiman, G. A., Klein, D. F., Hodge, S. E., Fyer, A. J., Weissman, M. M., & Knowles, J. A. (2004). Investigation of polymorphisms in the CREM gene in panic disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 126B, 111-5. PubMed
Weissman, M. M., Gross, R., Fyer, A., Heiman, G. A., Gameroff, M. J., Hodge, S. E., Kaufman, D., Kaplan, S. A., & Wickramaratne, P. J. (2004). Interstitial cystitis and panic disorder: a potential genetic syndrome. Archives of general psychiatry, 61, 273-9. PubMed
Hamilton, S. P., Slager, S. L., De Leon, A. B., Heiman, G. A., Klein, D. F., Hodge, S. E., Weissman, M. M., Fyer, A. J., & Knowles, J. A. (2004). Evidence for genetic linkage between a polymorphism in the adenosine 2A receptor and panic disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 29, 558-65. PubMed
Hamilton, S. P., Fyer, A. J., Durner, M., Heiman, G. A., Baisre de Leon, A., Hodge, S. E., Knowles, J. A., & Weissman, M. M. (2003). Further genetic evidence for a panic disorder syndrome mapping to chromosome 13q. Proceedings of the National Academy of Sciences of the United States of America, 100, 2550-5. PubMed
Ahsan, H., Hodge, S. E., Heiman, G. A., Begg, M. D., & Susser, E. S. (2002). Relative risk for genetic associations: the case-parent triad as a variant of case-cohort design. International journal of epidemiology, 31, 669-78. PubMed
Hamilton, S. P., Slager, S. L., Heiman, G. A., Deng, Z., Haghighi, F., Klein, D. F., Hodge, S. E., Weissman, M. M., Fyer, A. J., & Knowles, J. A. (2002). Evidence for a susceptibility locus for panic disorder near the catechol-O-methyltransferase gene on chromosome 22. Biological psychiatry, 51, 591-601. PubMed
Saunders-Pullman, R., Shriberg, J., Heiman, G., Raymond, D., Wendt, K., Kramer, P., Schilling, K., Kurlan, R., Klein, C., Ozelius, L. J., Risch, N. J., & Bressman, S. B. (2002). Myoclonus dystonia: possible association with obsessive-compulsive disorder and alcohol dependence. Neurology, 58, 242-5. PubMed
Hamilton, S. P., Slager, S. L., Helleby, L., Heiman, G. A., Klein, D. F., Hodge, S. E., Weissman, M. M., Fyer, A. J., & Knowles, J. A. (2001). No association or linkage between polymorphisms in the genes encoding cholecystokinin and the cholecystokinin B receptor and panic disorder. Molecular psychiatry, 6, 59-65. PubMed
Hamilton, S. P., Slager, S. L., Heiman, G. A., Haghighi, F., Klein, D. F., Hodge, S. E., Weissman, M. M., Fyer, A. J., & Knowles, J. A. (2000). No genetic linkage or association between a functional promoter polymorphism in the monoamine oxidase-A gene and panic disorder. Molecular psychiatry, 5, 465-6. PubMed
Hamilton, S. P., Haghighi, F., Heiman, G. A., Klein, D. F., Hodge, S. E., Fyer, A. J., Weissman, M. M., & Knowles, J. A. (2000). Investigation of dopamine receptor (DRD4) and dopamine transporter (DAT) polymorphisms for genetic linkage or association to panic disorder. American journal of medical genetics, 96, 324-30. PubMed
Weissman, M. M., Fyer, A. J., Haghighi, F., Heiman, G., Deng, Z., Hen, R., Hodge, S. E., & Knowles, J. A. (2000). Potential panic disorder syndrome: clinical and genetic linkage evidence. American journal of medical genetics, 96, 24-35. PubMed
Nygaard, T. G., Raymond, D., Chen, C., Nishino, I., Greene, P. E., Jennings, D., Heiman, G. A., Klein, C., Saunders-Pullman, R. J., Kramer, P., Ozelius, L. J., & Bressman, S. B. (1999). Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31. Annals of neurology, 46, 794-8. PubMed
Hamilton, S. P., Heiman, G. A., Haghighi, F., Mick, S., Klein, D. F., Hodge, S. E., Weissman, M. M., Fyer, A. J., & Knowles, J. A. (1999). Lack of genetic linkage or association between a functional serotonin transporter polymorphism and panic disorder. Psychiatric genetics, 9, 1-6. PubMed
Knowles, J. A., Fyer, A. J., Vieland, V. J., Weissman, M. M., Hodge, S. E., Heiman, G. A., Haghighi, F., De Jesus, G. M., Rassnick, H., Preud'homme-Rivelli, X., Austin, T., Cunjak, J., Mick, S., Fine, L. D., Woodley, K. A., Das, K., Maier, W., Adams, P. B., Freimer, N. B., Klein, D. F., & Gilliam, T. C. (1998). Results of a genome-wide genetic screen for panic disorder. American journal of medical genetics, 81, 139-47. PubMed
Almasy, L., Bressman, S. B., Raymond, D., Kramer, P. L., Greene, P. E., Heiman, G. A., Ford, B., Yount, J., De Leon, D., Chouinard, S., Saunders-Pullman, R., Brin, M. F., Kapoor, R. P., Jones, A. C., Shen, H., Fahn, S., Risch, N. J., & Nygaard, T. G. (1997). Idiopathic torsion dystonia linked to chromosome 8 in two Mennonite families. Annals of neurology, 42, 670-3. PubMed
Heiman, G. A., Hodge, S. E., Wickramaratne, P., & Hsu, H. (1996). Age-at-interview bias in anticipation studies: computer simulations and an example with panic disorder. Psychiatric genetics, 6, 61-6. PubMed
Bressman, S. B., Warner, T. T., Almasy, L., Uitti, R. J., Greene, P. E., Heiman, G. A., Raymond, D., Ford, B., De Leon, D., Fahn, S., Kramer, P. L., Risch, N. J., Maraganore, D. M., Nygaard, T. G., & Harding, A. E. (1996). Exclusion of the DYT1 locus in familial torticollis. Annals of neurology, 40, 681-4. PubMed
Bressman, S. B., Hunt, A. L., Heiman, G. A., Brin, M. F., Burke, R. E., Fahn, S., Trugman, J. M., De Leon, D., Kramer, P. L., & Wilhelmsen, K. C. (1994). Exclusion of the DYT1 locus in a non-Jewish family with early-onset dystonia. Movement disorders : official journal of the Movement Disorder Society, 9, 626-32. PubMed
Kramer, P. L., Heiman, G. A., Gasser, T., Ozelius, L. J., De Leon, D., Brin, M. F., Burke, R. E., Hewett, J., Hunt, A. L., & Moskowitz, C. (1994). The DYT1 gene on 9q34 is responsible for most cases of early limb-onset idiopathic torsion dystonia in non-Jews. American journal of human genetics, 55, 468-75. PubMed
Bressman, S. B., Heiman, G. A., Nygaard, T. G., Ozelius, L. J., Hunt, A. L., Brin, M. F., Gordon, M. F., Moskowitz, C. B., De Leon, D., & Burke, R. E. (1994). A study of idiopathic torsion dystonia in a non-Jewish family: evidence for genetic heterogeneity. Neurology, 44, 283-7. PubMed
Nygaard, T. G., Takahashi, H., Heiman, G. A., Snow, B. J., Fahn, S., & Calne, D. B. (1992). Long-term treatment response and fluorodopa positron emission tomographic scanning of parkinsonism in a family with dopa-responsive dystonia. Annals of neurology, 32, 603-8. PubMed